ON THE DEMONSTRATION OF STAPHYLOCOCCUS ENTEROTOXIN. 2. INVESTIGATIONS INTO THE EFFECT OF ENTEROTOXIN-FORMING STAPHYLOCOCCI ON CHICK EMBRYOS
ARMY BIOLOGICAL LABS FREDERICK MD
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The visible effects of the infection of 9 12, 12- and 16-day old chick embryos is similar to the picture that has been given so far in the literature on infection with staphylococci without enterotoxin production. The incubation of the tested strains also in a 30 percent CO2 atmosphere brought no further results in each test series other than the raising of the death rate. Micrococcus pyogenes var. albus -- accepted as apathogenous for chick embryos -- can have the same toxic effectiveness as micrococcus pyogenes var. aureus. The infection test with microccus pyogenes var. albus on incubated hen eggs should therefore be employed particularly in persistent infections cystitis, conjunctivitis and as a pathogenicity test in the demonstration of this microorganism in the fluid or the circulating blood. On treating infected chick embryos with erythromycin a clear effect of this antibiotic was perceptible.