Accession Number:

AD0837476

Title:

CANCEROLOGY. IMMUNOFLUORESCENCE STUDY OF THE ANTIGENIC PROPERTIES OF THE ATYPICAL EPITHELIOMA OF GUERIN'S RAT T 8,

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

• Herbeuval, Rene
• Duheille, Jean
• Bellut, Francoise

Report Date:

1966-09-13

Pagination or Media Count:

2.0

Abstract:

A fluorescent immune serum prepared against a microsomial fraction of the atypical epithelioma of Guerins T 8 rat fixes electively on the tumor. The cells in the tumor are more marked as they are more evolved. The different controls performed confirm the immunological specificity of the obtained marking. The results obtained testify to the existence of a specific antigen for the atypical epithelioma of Guerins T 8, an antigen which is more abundant as the cells maturation state is advanced. The nature of this antigen is still unknown but it does not seem to be of viral origin. The electron microscope study of the tumor shows only rare and inconstant particles having viral appearance. Author

Descriptors:

• *NEOPLASMS
• ANTIGENS
• ANTIBODIES
• IMMUNE SERUMS
• FLUORESCENT ANTIBODY TECHNIQUES
• ELECTRON MICROSCOPY
• FRANCE

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE