Accession Number:

AD0837129

Title:

HOST INFLUENCE ON THE CHARACTERISTICS OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS

Descriptive Note:

Corporate Author:

FORT DETRICK FREDERICK MD

Personal Author(s):

• Heydrick, Fred P.
• Wachter, Ralph F.
• Dwyer, James X.

Report Date:

1968-01-01

Pagination or Media Count:

14.0

Abstract:

One objective of the virus research program is to demonstrate that physiochemical and biological properties of viruses can be altered by selection of, or modification of, the host system in which the virus is propagated, with the ultimate goal of obtaining viral agents whose biological characteristics can be predicted andor controlled in the growth environment. An approach to this objective was to study the relationship of changes in lipid composition of Venezuelan equine encephalitis VEE virus that occur when the virus is propagated in different hosts and to determine if a correlation exists between the changes observed and the biological characteristics of the virus. Comprehensive analyses of the lipid of VEE virus propagated in a number of different hosts were performed.

Descriptors:

• *VENEZUELAN EQUINE ENCEPHALOMYELITIS VIRUS
• EMBRYONATED EGG TECHNIQUE
• FATTY ACIDS
• GAS CHROMATOGRAPHY
• GROWTH(PHYSIOLOGY)
• LIPIDS
• PURIFICATION
• TISSUE CULTURE CELLS

Subject Categories:

• Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE