Accession Number:

AD0836720

Title:

STUDY OF THE EFFECTS OF LYOPHILIZATION ON BILIARY CATATONIA

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1964-06-08

Pagination or Media Count:

8.0

Abstract:

The examination of the bile of eight patients suffering from mental troubles show that lyophilization in a general fashion clearly modified the pathogenic action of biles in animals. Certain biles producing catatonia before lyophilization lose this property after lyophilization. The same is true for the paralyzing and general toxic action, especially in cases 5 and 6 where the fresh bile caused paralysis and death of the animal before lyophilization while after lyophilization these same biles had no effect or else caused only a slight passing loss of initiative. The same is true of the high optical density of toxic biles this optical density also goes down after lyophilization. These results favor the hypothesis that considers the biliary catatonia producing agent as a particularly fragile product.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE