Accession Number:

AD0836295

Title:

ACTIVATION OF SIGMA-PROTOTOXIN OF TYPE D CL. PERFRINGENS WITH PROTEINASES OF A AND D TYPES,

Descriptive Note:

Corporate Author:

ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER CHARLOTTESVILLE VA

Report Date:

1967-01-01

Pagination or Media Count:

7.0

Abstract:

The goal of this work was to study the possibility of activating sigma -prototoxin of D-type Cl. perffringens by proteinases of Cl. perfringens of the A and D types. A necessary condition in performing such a study is obtaining each of the ingredients of the sample without any admixture of another ingredient. There have been numerous studies on the purification of sigma -prototoxin of the D-type Cl. perfringens. At the present time, this prototoxin has been obtained in the form of a preparation homogeneous, immunologically, during studies in an ultracentrifuge Habeeb, 1963, and by some researchers in the form of crystals Verwoerd, 1960 Thomson, 1962, 1963. However, studies by the method of electrophoresis in starch and acrylamide gels revealed its heterogeneity. Author

Subject Categories:

  • Toxicology
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE