Accession Number:

AD0836209

Title:

FURTHER REPORTS ON THE DISTRIBUTION OF NITROGEN-CONTAINING MATERIALS IN THE BLOOD

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1964-01-06

Pagination or Media Count:

21.0

Abstract:

These studies show that 1 Of the nitrogen from the urine of the sick that was not precipitable by phosphotungstic acid, 95.85-98.36 existed as urea. 2 Of the nitrogen-containing materials precipitable by phosphotungstic acid, 5.16-8.51 existed as purine materials and ammonia compounds. 3 Of the total nitrogen in urine, 83.93-91.07 originated from urea. 4 Amino acid nitrogen accounted for 1.52-3.61 of the total nitrogen. 5 The amount of total nitrogen, multiplied by two, gives the amount of urea in albumen-free urine with sufficient accuracy for clinical investigations. 6 According to the relations found in pathological urine and from the two experiments on normal humans, about 1.5-3 at the most of the total nitrogen should consist of amino acid nitrogen this quantity can be increased by certain nourishment, for example the introduction of materials containing benzoic acid. In liver diseases, typhus abdominalis, diabetes mellitus, even in individual cases of Basedow illness, the elimination of amino acid nitrogen increased. This can amount to 0.64 g in the daily quantity of urine during diabetes, 0.50 g in typhus.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE