ACTUAL PROBLEMS OF ANTIVIRAL CHEMOTHERAPY
Army Biological Labs FORT DETRICK United States
Pagination or Media Count:
Antiviral chemotherapy resides in the research of chemical products capable of modifying, with a given mechanism, the complex series of events which accompany, in the nucleous of the cell and of the nucleous of the whole animal, the development of the viral infection. This is a question of the adsorption of the virus on the cell, of its multiplication, of its liberation, of its propagation from one cell to the next or the lesions and the symptoms which this infection causes directly or indirectly. Antiviral chemotherapy, in contrast to antibacterial chemotherapy has as its essential objective not only the infectious particle itself but also the association virus-cell, the viral infection being only an alteration of the normal cell function by the introduction of a strange genetic material capable of deflecting for its own benefit certain synthetic activities of the cell. The antiviral classification is based essentially on the chemical nature and the probable chemical activity of the products considered.