SYNTHETIC STUDIES ON PEPTIDES.
Final comprehensive rept. Jan 65-Dec 66,
PITTSBURGH UNIV PA PROTEIN RESEARCH LAB
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A series of N-benzyloxycarbonyl- peptide t-butoxyhydrazides has been prepared corresponding to the amino acid sequence of the enzyme Ribonuclease T sub 1. These peptide derivatives span the sequence of the enzyme from positions 48-104. They will be used in an attempt to assemble the polypeptide chain of the entire enzyme 104 residues.