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STUDIES ON THE AGAR-GEL PRECIPITIN-INHIBITION TEST FOR COCCIDIOIDOMYCOSIS: II. SEROLOGICAL TEST ANTIGEN STUDIES IN AGAR-GEL,
FORT DETRICK FREDERICK MD
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In this study of saprophytic and parasitic growth-phase extracts of Coccidioides immitis, an antigen from the spherule culture supernatant detected a specific antibody in heretofore serologically negative suspect coccidioidomycosis human sera when diffused in agar-gel. This antigen-antibody reaction occurred also in some of the serologically positive human coccidioidomycosis sera. This study indicates that for a complete serodiagnosis of this disease, this antigen-antibody reaction should be used as a routine serological test. Author
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