ORGAN WEIGHT CHANGES IN GRID-SHIELDED X-IRRADIATED RATS,
ARMY MEDICAL RESEARCH LAB FORT KNOX KY
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An investigation was made of the role of certain organs on the beneficial effect afforded by grid shielding on the survival of X-irradiated rats. The results confirm the beneficial effect of partial shielding by grids on survival of X-irradiated rats. For rats receiving equal midline doses through grids of constant per cent open area, there is increased survival with decreasing aperture size. A delay was noted in the timely distribution of intestinal deaths for smaller aperture size grids. This delay was not reflected by intestinal weight changes. Small changes, in some cases significant, were observed in spleen, kidney, and liver weights, although these changes did not appear to follow survival pattern. It is recommended that the work of Bauer et al be extended to include blood electrophoretic studies on rats receiving equal midline doses of X-rays through grids having same per cent open area but different aperture size.
- Anatomy and Physiology