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Accession Number:
AD0806400
Title:
EFFECTS OF THE COLD PRESSOR TEST ON GLOMERULAR FILTRATION AND EFFECTIVE RENAL PLASMA FLOW,
Descriptive Note:
Corporate Author:
ARMY MEDICAL RESEARCH LAB FORT KNOX KY
Report Date:
1947-10-27
Pagination or Media Count:
7.0
Abstract:
Studies were made of the effects of the cold pressor test on renal function. Seven male volunteers who had no history of renal disease served as subjects. Glomerular filtration as measured by mannitol clearance and effective renal plasma flow as measured by sodium para-aminohippurate clearance were determined before, during and after immersion of the foot in ice water at 1 C for 15 minutes. In 6 out of 7 subjects both glomerular filtration rate and effective renal plasma flow decreased either during the application of the cold stimulus or within approximately 30 minutes thereafter. In no subject did the effect persist longer. The average decrease in glomerular filtration rate and effective renal plasma flow, as compared with the control values, were 14 and 21, respectively. Author
Distribution Statement:
APPROVED FOR PUBLIC RELEASE