Accession Number:

AD0804069

Title:

Z(EXPERIMENTAL)ZINFECTION OF COYOTE PUPS WITH VENEZUELAN EQUINE ENCEPHALITIS VIRUS.

Descriptive Note:

Technical rept.,

Corporate Author:

DUGWAY PROVING GROUND UT BIOLOGICAL DIV

Report Date:

1966-11-01

Pagination or Media Count:

14.0

Abstract:

An investigation was undertaken to determine the disposition of coyotes to infection by the virus of Venezuelan equine encephalomyelitis, and also to determine onset, height and duration of haemagglutination inhibiting, complement-fixing and virus-neutralizing antibody. In this initial report, it is shown that young coyotes were highly susceptible to the epidemic strain of VEE virus used, and that they developed a dose-independent viremia lasting for an average of 3.6 days in 1 to 2 months-old pups, and 2.8 days in 6 to 7 months-old pups. Less than one mouse intra cerebral medial dose MICLD50 may initiate infection within 24 hours. Infection with strain of VEE virus led to a characteristic symptomatology, but was characterized by a low incidence of lethality even in very young animals. These results indicate that the coyote may serve as a short term source of VEE virus in the natural infection chain. Although the coyote does occur over a wide geographic range including endemic areas, its role as a link in the dissemination chain leading to human communities may nevertheless be minimal because of its low population density. Author

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE