A Quantitative Determination of the Rate of Bone Growth into a Porous Ceramic Material.
Technical rept. no. 5, 1 May 73-30 Jun 74,
CLEMSON UNIV S C COLL OF ENGINEERING
Pagination or Media Count:
The growth of mineralized bone into porous materials may eventually lead to the development of prosthetic or reconstructive devices which depend upon this ingrowth for their stabilization in vivo. If porous implants are to ever become successful, it will be necessary to know the rate at which bone proliferates in the implant porosity. The objectives of this investigation were to develop a method for the quantification of the rate of bone growth into a porous material and to determine such a rate for one particular porous ceramic material. The amount of mineralized bone growth into the porous ceramic increased with time for each pore structure examined however, no significant relationship between the volume percent of bone ingrowth and pore structure was found. The interfacial pores of all pellets approached complete ingrowth sometime between 8 and 16 weeks post-operatively. Lastly, for all pore structures and time periods, a linear volume rate of bone ingrowth was calculated to be 0.222 cu mm boneday. Modified author abstract
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