Technical Manual for Identification of Hemoglobin Variants and Deficiency of Glucose-6-Phosphate Dehydrogenase.
Medical research progress rept. no. 2,
NAVAL MEDICAL RESEARCH INST BETHESDA MD
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The manual of laboratory methodology was developed to provide basic information for testing programs for two genetic characteristics, variant hemoglobins and deficiency of glucose-6-phosphate dehydrogenase G6Pd. The first section describes the approach to be used for voluntary programs primarily concerned with genetic counseling. In these programs, individual patients will generally request medical advice on the mode of inheritance of abnormal hemoglobins and the consequence of their hemoglobin phenotype on possible children. It must be emphasized that these programs are strictly voluntary and require electrophoresis as the primary laboratory method. The second section deals with testing of all entering military personnel for the purposes of industrial health safety. In this program, all persons entering on active duty are tested by automated techniques for the presence of hemoglobin S andor deficiency of erythrocyte G6PD. Modified author abstract