Technetium-99m Diphosphonate Scintigraphy to Detect Early Avascular Necrosis of the Hip
ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD
Pagination or Media Count:
Ten National Naval Medical Center patients ages 20 to 62 and selected by history as having a high probability of early aseptic necrosis of the hip received bilateral tomographic hip technetium scans. The technetium-99m on a sodium diphosphonate carrier was injected between 2 and 3 hours prior to the scanning procedure. The gamma camera was centered over the hip, and tomographic cuts were made to approximately 500,000 counts each. The urinary bladder contained the greatest activity in most cases which usually required the patient to void prior to the scan. Once the tomographic level of interest was ascertained, it was used identically for both hips. The data were then processed on a MED-II computer. Of the 10 studies, there were four true positives, four true negatives, and one each false negative and false positive. Although this series of patients is too small to draw any definite conclusions as to the accuracy of the method, it is apparent that it is a potentially effective means of detecting the presence of aseptic necrosis prior to radiographic changes.
- Medicine and Medical Research