Chemical and Immunochemical Characteristics of the Whooping-Cough Allergen Obtained by Water-Ether Extraction,
FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO
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The results of the investigation showed that the Mashkov water-ether extraction method makes it possible to obtain a preparation, possessing the specific properties of the whooping cough allergen. However, in view of the low yield of the preparation, some changes in the original procedure were introduced, which increased the yield of protein in the allergen preparations, and increased their serological activity. Research on the chemical and immunochemical properties of the whooping cough allergen preparations showed that they are complexes of proteins and polysaccharides. Five antigenic components were detected in immunochemical reactions.