Pulmonary Vascular Impedance in Chronic Pulmonary Hypertension.
OKLAHOMA UNIV HEALTH SCIENCES CENTER OKLAHOMA CITY DEPT OF SURGERY
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Results suggest that in pulmonary hypertension there are significant changes in the pulmonary vascular input impedance and that these changes are compatable with a more proximal major reflecting site indicative of the obstruction of small pulmonary arteries by emboli or arteriolar narrowing. There is also evidence of increased stiffness of the proximal pulmonary artery probably as the result of the increased distending pressure. This decrease in pulmonary artery compliance has significant consequences to the heart as a significant increase in hydraulic power is associated with pulsatile flow in pulmonary hypertension. These results do not confirm the relationship of decreased pulmonary artery compliance to a histologic alteration in the vessel wall since the changes demonstrated can be explained by distension alone. Modified author abstract
- Anatomy and Physiology
- Medicine and Medical Research