Accession Number:

AD0784013

Title:

Effectiveness of Different Methods of Specific Desensitization by Microbial Allergens

Descriptive Note:

Technical Report

Corporate Author:

AIR FORCE SYSTEMS COMMAND WRIGHT-PATTERSON AFB OH WRIGHT-PATTERSON AFB

Personal Author(s):

Report Date:

1974-07-24

Pagination or Media Count:

13.0

Abstract:

The significance of microbial allergy with bronchial asthma is recognized by many researchers. Several widely accepted methods for sepcific desensitization by microbial antigens are examined. The following types of microbial antigens were employed soluble, which is a supernatant liquid of microbial suspension not containing microbial cells full antigens which include microbial cells, and the products of their metabolism. The full antigens of all autostrains isolated from sputum, heterovaccines, which are a mixture of antigens on which positive skin reactions were detected on the patient, and also by a combined vaccine, which is a standard mixture of all forms of microorganisms, most frequently sown from the sputum of patients with bronchial asthma. Treatment was carried out subcutaneously and intracutaneously. The conclusions were as follows The soluble noncellular microbial allergens possess low therapeutic effectiveness considerably inferior to full antigens. The effectiveness of autovaccines, heterovaccines, and a combined vaccine is approximately identical.

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE