Accession Number:

AD0781498

Title:

Effect of Storage on Oxygen Transport in Blood Obtained from Man, Dog and Monkey.

Descriptive Note:

Progress rept.,

Corporate Author:

ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s):

• Shields,Charles E.
• Meixner,David E.
• Bratton,Joseph F.
• Brooks,Daniel E.
• Zegna,Angelo I.

Report Date:

1974-04-16

Pagination or Media Count:

14.0

Abstract:

Red cells obtained from human, monkey and canine subjects were stored in acid-citrate-dextrose ACD over a six week period and periodically tested for mid saturation point P50, pH, adenosine triphosphate ATP and 2,3-diphosphoglycerate DPG levels. In addition, blood obtained from dogs kept chronically anemic and also from those undergoing daily exercise was stored and compared to the other groups. The anemic and exercised groups were found to have higher than normal DPG values, with only the exercise group showing corresponding elevation in P50 levels. The results showed a general decrease in all tested values with storage. Modified author abstract

Descriptors:

• *BLOOD PRESERVATION
• ERYTHROCYTES
• HUMANS
• MONKEYS
• DOGS
• OXYGEN
• TRANSPORTABLE
• PH FACTOR
• ADENOSINE PHOSPHATES
• BLOOD DONORS
• ANEMIAS
• EXERCISE(PHYSIOLOGY)

Subject Categories:

• Anatomy and Physiology
• Medical Facilities, Equipment and Supplies

Distribution Statement:

APPROVED FOR PUBLIC RELEASE