Accession Number:

AD0780117

Title:

Development of Mosquito Repellents Having Increased Protection Time in Man.

Descriptive Note:

Annual rept. 1 Jul 73-15 Mar 74,

Corporate Author:

STANFORD RESEARCH INST MENLO PARK CA

Personal Author(s):

• Skinner, W. A.
• Johnson, Howard L.
• Tong, H. C.

Report Date:

1974-03-15

Pagination or Media Count:

66.0

Abstract:

Synthetic topical repellents were prepared, following previously reported leads that resulted from intrinsic repellency studies and from Stanford Research Institute SRI computed-coded USDA compounds. The most promising structural area for topical repellency continues to be glycol ether derivatives, although the carbamide, 2,4-thiazolidinedione, and quinoxaline areas are also of interest. Efforts were directed toward polymer formulations of SRI glycol ethers to improve their wash-off characteristics and cosmetic acceptability. These studies range from the typical film-formers to carbowax stick-type formulations. Large samples of two 2,4-thiazolidinediones were synthesized for toxicologic evaluation. Modified author abstract

Descriptors:

• *CULICIDAE
• *INSECT REPELLENTS
• ETHERS
• BEHAVIOR
• HUMANS
• PROTECTION
• GLYCOLS
• THIAZOLES
• QUINOLINES
• SULFONAMIDES
• TOXICOLOGY
• HUMANS

Subject Categories:

• Hygiene and Sanitation
• Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE