Volume Conditioned Stimuli Affecting Salt and Water Excretion.
Interim scientific rept. 1 Jul 71-30 Nov 73,
FREIE UNIVERSITAET BERLIN (WEST GERMANY) PHYSIOLOGISCHES INSTITUT
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The following investigations were conducted to analyze certain aspects of plasma volume control and simulated weightlessness by whole body immersion in a thermo-indifferent bath. Upon immersion the central venous pressure rises to about 15 mmHg. Rontgenometric studies reveal an increase of heart volume by 20 ml, when a standing subject was immersed. The effective compliance of the circulation of man was determined together with the compliance of the intrathoracic vascular compartment. The former is 2 - 3 mlmmHgkg, the latter 0.9 - 1.2 mlmmHgkg. Using radio-isotope techniques the redistribution of the extracellular fluid volume between interstitial fluid volume and plasma volume was investigated together with central venous pressure under various states of hydration. Modified author abstract
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