Aldehyde Treatment of Cyanide Poisoning in Mice
Technical rept. Sep-Oct 1973
EDGEWOOD ARSENAL ABERDEEN PROVING GROUND MD
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Eight aldehydes have been tested as therapeutic compounds for cyanide poisoning in mice. The most effective are glyoxal trimer and glyceraldehyde. These increase the LD50 2.5 to 3 times. No correlation was found between activation of the carbonyl group resulting from nearby electron-withdrawing substituents and therapeutic value.