Accession Number:

AD0779410

Title:

Functional Role of Hypothalamic Histamine: Release of Vasopressin.

Descriptive Note:

Technical rept. Jun 72-Sep 73,

Corporate Author:

EDGEWOOD ARSENAL ABERDEEN PROVING GROUND MD

Personal Author(s):

Report Date:

1974-05-01

Pagination or Media Count:

14.0

Abstract:

Following the injection of histamine directly into the supraoptic nucleus, a dramatic decrease in urine flow ensued. This oliguria, and the concomitant increase in urine concentration, reflect the release of vasopressin. This histaminergic effect could be inhibited by an antihistamine, but not an antinicotinic, antimuscarinic or adrenergic blocker. It is suggested that hypothalamic histamine plays an important role in the release of vasopressin. Author

Subject Categories:

  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE