Accession Number:

AD0779130

Title:

Study of the Reaction Mechanism of Blood Neutrophils to Antigen,

Descriptive Note:

Corporate Author:

FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s):

Report Date:

1974-04-08

Pagination or Media Count:

15.0

Abstract:

The increased sensitivity of neutrophils to allergen is realized against the background of quantitative shifts in the enzyme composition of cells and is the consequence of the appearance of the specific antigenic complexes in the organism. The reaction of neutrophils to allergen begins from the intense amoeboid activity, which subsequently is accompanied by subcellular degenerative changes. The conditions of manifestation of sensitivity to allergen tuberculin on the part of the blood neutrophils and outer integuments are ambiguous. Histamine in vitro does not cause the amoeboid reaction of the sensitized neutrophils and does not change its intensity during the incubation of blood with allergen.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE