Accession Number:

AD0777918

Title:

Investigation of Fluorescence Based Systems for Detection of Morphine in Urine.

Descriptive Note:

Final rept. 1 Dec 73-31 Jan 74,

Corporate Author:

BATTELLE COLUMBUS LABS OHIO

Personal Author(s):

• Knowlton,David A.
• Neher,Maynard B.

Report Date:

1974-07-31

Pagination or Media Count:

24.0

Abstract:

Conditions for extraction of morphine free base from urine were optimized. Procedures for derivatization of the morphine extracted from urine with dansyl chloride and also with isatoic anhydride were developed. Methods for separation of the fluorescent morphine from other urinary constituents were investigated. Author

Descriptors:

• *MORPHINE
• *URINE
• CHEMICAL REACTIONS
• CHEMICAL DERIVATIVES
• SOLVENT EXTRACTION
• FLUORESCENCE

Subject Categories:

• Biochemistry
• Pharmacology
• Organic Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE