A Method of Examination of the Direct Action of Allergens on the Function of the Adrenal Cortex under Experimental Conditions,
FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO
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Under conditions of prolonged perfusion of the adrenal glands of dogs in situ by an artificial fluid, preliminary hypophysectomy is not needed. The stressed stimulation of the secretion of corticosteroids by the adrenal glands of intact dogs is removed by washing of the adrenal glands over the period of the first 30-40 minutes of perfusion, after which a more or less constant level of their secretion is established with some trend toward a reduction in the production of cortisol. At this time the adrenal glands retain sensitivity to adrenal cortex hormones.
- Anatomy and Physiology