An Investigation of Bonding Mechanisms at the Interface of a Prosthetic Material.
Rept. no. 4 (Annual), 1 Sep 72-31 Aug 73,
FLORIDA UNIV GAINESVILLE DEPT OF MATERIALS SCIENCE AND ENGINEERING
Pagination or Media Count:
Specially designed glasses and glass-ceramic implants containing Na, Ca, P, and Si ions develop a bond between the material and living bone. The formation of the interfacial bond involves the development of a SiO2 gel by loss of Na ions from the surface into the extracellular fluids. Bone growing cells create collagen fibers which become entrapped in the SiO2-rich gel in 3-4 weeks. In 4-6 weeks Ca, P migration through the surface gel produces large hydroxyapatite-like crystals which interlock with naturally mineralizing bone forming a stable bond. This interfacial bonding mechanism is established using transmission electron microscopy, ion-milling Auger spectroscopy, SEM with x-ray analysis, ion solution analysis, and various polypeptide adsorbtion studies. Techniques and computer programs for the calculation of stress in arbitrary multiply-connected cross sections have been developed and are being applied to the mechanical data obtained from the monkey experiments. Preliminary data on the variability of paired bones for biomechanical studies have been statistically evaluated and presented. Modified author abstract
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