Accession Number:

AD0772447

Title:

Study of Virulence and Immunogenic Properties in Recombinants of the Plague Microbe: Imparted Episomal Polyresistance to Antibiotics as a Result of Conjugation with a Strain of Intestinal Bacillus Possessing the R Episome,

Descriptive Note:

Corporate Author:

ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER CHARLOTTESVILLE VA

Personal Author(s):

Report Date:

1973-07-20

Pagination or Media Count:

9.0

Abstract:

Recombinants resistant to streptomycin, chloramphenicol, and tetracycline were obtained possessing the high virulence and immunogenic properties of the receptor strain of plague microbe Pasteurella pestis. Conjugation of a less virulent plague microbe strain with polyresistant E. coli resulted in a loss of virulence due to genetic heterogeneity of the receptor strain rather than to the effect of the R-episome received. Author

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE