Accession Number:

AD0770903

Title:

The Antiviral Action of Ribonuclease

Descriptive Note:

Technical Report

Corporate Author:

ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD FORT DETRICK

Personal Author(s):

Report Date:

1970-01-01

Pagination or Media Count:

11.0

Abstract:

With the use of a model of the virus of Venezuelan equine encephalomyelitis, the inhibiting effect of a preparation of pancreatic ribonuclease on the accumulation and infectious and hemagglutinating activity of the virus, and interferon production in chicken embryo fibroblast culture were determined. Statistical processing confirmed a high degree of correlation in the suppression of all three types of activity. The mechanism of virus-inhibiting action of ribonuclease is discussed. The article includes two tables, two illustrations and a bibliography of 16 titles.

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE