Accession Number:

AD0768943

Title:

Darminvaginationen bei Krallenaffen der Species Saguinus (Oedipomidas) Oedipus als Moegliche Folge von Infektionen mit Adenoviren (Intestinal Invagination in Monkeys of the Species Saguinus (Oedipomidas) Oedipus as a Possible Consequence of Adenovirus Infection),

Descriptive Note:

Corporate Author:

ROBERT KOCH-INSTITUT BERLIN (WEST GERMANY)

Personal Author(s):

Report Date:

1969-01-24

Pagination or Media Count:

11.0

Abstract:

During the course of investigations on experimentally induced hepatitis in monkeys of the species Saguinus Oedipomidas oedipus, increased incidence of intestinal invaginations has been observed. The monkeys had been infected with adenovirsu or with sera of monkeys suffering from experimentally produced hepatitis. Previously it could be demonstrated that these sera contained in all probability adenovirus. Non-infected monkeys, however, have been found to be infected with adenovirus only in very rare cases. Intestinal invagination was seen in 24 out of 204 infected monkeys and in 2 out of 450 non-infected monkeys. Intranuclear inclusions, similar to adenovirus inclusions were demonstrated in the intestinal epithelium of infected monkeys, both with invagination and without this symptom. Adenovirus antigen was demonstrated in the intestinal epithelium of some of these monkeys by means of indirect immunofluorescence. Virus isolations could not be made. Nevertheless, the findings described in the present paper might be indicative for adenovirus multiplication in the intestinal epthelium of experimentally infected monkeys. Modified author abstract

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE