Accession Number:
AD0768921
Title:
Baroreceptor Reflex Response to Phenylephrine and Carotid Occlusion in Monkeys Receiving 1000 Rads Cobalt-60
Descriptive Note:
Topical rept.
Corporate Author:
LOVELACE FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH ALBUQUERQUE NM
Personal Author(s):
Report Date:
1973-08-10
Pagination or Media Count:
24.0
Abstract:
Nine conscious monkeys received phenylephrine and carotid occlusion test of baroreflex function before and after 1000 rads Cobalt-60 exposure dose rate 170 radsmin.. During the early postradiation minutes, concomitantly with hypotension and tachycardia, both baroreflex tests revealed depressed sensitivity diminished blood pressure and heart rate changes. After 8-15 minutes postradiation, the phenylephrine, but not the occlusion test demonstrated a reversal to significant baroreceptor hypersensitivity which persisted 24 hours or more. No failure of the baroreflex mechanisms was suggested.
Descriptors:
Subject Categories:
- Radiobiology