Accession Number:

AD0768868

Title:

Rejection Mechanisms in Corneal Transplantation.

Descriptive Note:

Final scientific rept.,

Corporate Author:

BOSTON UNIV MASS SCHOOL OF MEDICINE

Report Date:

1973-10-15

Pagination or Media Count:

7.0

Abstract:

The report details efforts to characterize the transplantation antigens of the cornea as encountered in xenogeneic keratoplasty. Three protein factions have been isolated from the cornea. Each has been shown to possess transplantation antigen activity as demonstrated by its ability to induce a specific sensitization resulting in the accelerated destruction of a subsequent corneal graft. The antigenic fractions are also capable of stimulating the production of humoral antibodies. The relationship between the transplantation immunity and the antibody response will be discussed. Author

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE