Rejection Mechanisms in Corneal Transplantation.
Final scientific rept.,
BOSTON UNIV MASS SCHOOL OF MEDICINE
Pagination or Media Count:
The report details efforts to characterize the transplantation antigens of the cornea as encountered in xenogeneic keratoplasty. Three protein factions have been isolated from the cornea. Each has been shown to possess transplantation antigen activity as demonstrated by its ability to induce a specific sensitization resulting in the accelerated destruction of a subsequent corneal graft. The antigenic fractions are also capable of stimulating the production of humoral antibodies. The relationship between the transplantation immunity and the antibody response will be discussed. Author
- Medicine and Medical Research