Accession Number:

AD0768824

Title:

Experimenteller Beitrag zur Pathogenese der Tollwut (Experimental Contribution to the Pathogenesis of Rabies),

Descriptive Note:

Corporate Author:

ROBERT KOCH-INSTITUT BERLIN (WEST GERMANY)

Personal Author(s):

Report Date:

1969-03-19

Pagination or Media Count:

13.0

Abstract:

The authors report on pathogenesis experiments performed on Syrian golden hamsters, Chinese dwarf hamsters and albino mice, using plantar adapted virus fixe CVS. Transmission of virus via placenta was not observed after intraplantar infection of gravid mice. Following intraplantar infection of Syrian golden hamsters and Chinese dwarf hamsters virus could be demonstrated at the site of inoculation from the moment of administration till the end of the experiment. Passive immune therapy applied to albino mice and Chinese dwarf hamsters after plantar infection yielded the following results A single serum dose administered one hour prior to infection proved capable of preventing rabies infection in experimental animals. If passive immunization occurred after infection, only part of the animals were protected. Modified author abstract

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE