Entwichlunsphasen, Entwicklungszyklen und Systematische Stellung von Toxoplasma Gondii (Developmental Cycles, Development Phases and Systematic Position of Toxoplasma Gondii),
ROBERT KOCH-INSTITUT BERLIN (WEST GERMANY)
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The different forms of Toxoplasma gondii shown in the paper of Werner and Voss were assigned in the present paper to the specific developmental phases of the parasite. There are five developmental phases Proliferative multiplication phase cyst phase agamogony Schizogony gamogony sporogony. These five phases together form the fundamental cycle. The observed variability within this cycle is stressed. The phases of unsexual development prefer the tissue of the reticulo-endothelial system. the cyst phase the skeletal muscles and the Central Nervous System CNS, and the phases of sexual development the epithelium of the small intestine. The time intervals after infection when the individual developmental phases of toxoplasms may be observed in the tissue were shown to depend upon the parasitic phase used for infection and upon the path of infection. Demonstration of the complete sexual developmental course up to the formation of mature, infective oocysts was successful so far only in the domestic cat.