Biphasic Occurrence of IgM-Forming Cells in the Intestine after Oral Immunization,
ROBERT KOCH-INSTITUT BERLIN (WEST GERMANY)
Pagination or Media Count:
The lamina propria has its own lymphatic organ with immunocompetent cells. The secretions of the mucous membranes contain, besides IgG and IgM, predominantly immunoglobulin IgA, which seems to be produced in the lymphatic part of the lamina propria and secreted into the intestinal lumen. Here the epithelial cells may play a special role by producing the so-called T piece that links 7S IgA to an 11S unit. Reported are IgM-producing cells which are demonstrable in the lamina propria by the direct Jerne technique and which occur biphasically after oral immunization.
- Anatomy and Physiology