Accession Number:

AD0768810

Title:

Bakteriologisch-Serologische Untersuchungen an Experimentell mit S. Typhil Infizierten Meerschweinchen (Typhusbakterienausscheider) (Bacteriological and Seriological Investigations on Guinea Pigs, Experimentally Infected with S. Typhi (Bacterial Excretors),

Descriptive Note:

Corporate Author:

ROBERT KOCH-INSTITUT BERLIN (WEST GERMANY)

Personal Author(s):

Report Date:

1968-10-12

Pagination or Media Count:

9.0

Abstract:

Investigations were carried out on 151 guinea pigs previously infected with Salmonella typhi through the gallbladder. The animals were examined for their excreting of Salmonella typhi as well as for their agglutination titers. Depending on the duration of the observation period excretion of Salmonella typhi was demonstrated in the individual groups as long as 103, 114, 208, 302, 315, and 351 days following infection. In a great number of animals the Widal reaction remained positive till the end of the experimental period, which means as long as 100, 114, 208, 302, 315 and 351 days after infection. From these observations follows that the above described method of testing represents a suitable model for experiments on the sanitation of typhoid carriers. The experiments, it is true, were completed quite a long time ago, however, still may be of some interest for chemotherapists, since so far the problem has remained unsolved. In the present case all sanitation trials performed on the animals with chloromycetin, even after equal treatment with omnadin, ended in failure. Author

Subject Categories:

  • Hygiene and Sanitation
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE