Genetic and Biochemical Studies of Drug Resistance in Pathogenic Bacteria.
Rept. no. 2 (Annual), 15 Jun 72-14 Jun 73,
INSTITUTE OF MICROBIAL CHEMISTRY TOKYO (JAPAN)
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Collected ions have been made of many bacterial strains from patients at hospitals which are geographically dispersed in Japan, including Shigella, other gram-negative bacteria and staphylococci. The biological and biochemical properties are studied according to the usual bacterial technics. Resistance to about 30 antibacterial agents was assayed, and biochemical and genetic studies of bacterial drug-resistance were conducted. This report discusses the genetic and biochemical problems of drug-resistance in bacteria.