Prostaglandins and the Lung
OKLAHOMA UNIV FOUNDATION INC OKLAHOMA CITY OKLAHOMA CITY United States
Pagination or Media Count:
The prostaglandins exert multiple potent pharmacological actions on different organs and tissues including the respiratory system. Although it is rather premature to conclude the precise physiological and pathophysiological roles of prostaglandins at the present time, a large number of recent observations implicate a close relationship between prostaglandins and pathogenesis and clinical manifestations of pulmonary disease. With reasonable certainty, the pathophysiological roles of the prostaglandins in respiratory disease will be clarified, along with a better understanding of pulmonary disease mechanisms. Furthermore, one can anticipate the synthesis of more potent and specific prostaglandin antagonists which may prove valuable in the treatment of respiratory disease.