Cochlear Histopathology in the Chinchilla after Exposure to Impulse Noise.
ARMY MEDICAL RESEARCH LAB FORT KNOX KY
Pagination or Media Count:
Chinchillas were exposed to 1-500 impulses and their cochleae were stained with osmic acid and dissected. The number of damaged hair cells in each half turn of the cochlea was counted by examination under a phase-contrast microscope. Insignificant hair cell loss was seen over the range of exposures of from 1-40 impulses. However, exposure to 500 impulses did result in large amounts of damage in the basal half turns of two out of three chinchillas. The pattern of loss seen was different from that seen after comparable exposures in the monkey. It was suggested that the damage produced in the chinchillas middle ear by exposure to few impulses protected these cochleae from further damage, while the absence of such middle ear damage in the monkey resulted in the cochleae receiving the full trauma of the impulse with a resulting larger amount of hair cell damage in the monkey. Comparisons to humans were also drawn. Author
- Medicine and Medical Research
- Stress Physiology