Accession Number:

AD0765929

Title:

The Effects of Washing, EDTA, Magnesium and Calcium on Oxidative Phosphorylation and Respiratory Rates of Mitochondria from Heat- and Cold-Acclimated Rats.

Descriptive Note:

Research rept.,

Corporate Author:

DEFENCE AND CIVIL INST OF ENVIRONMENTAL MEDICINE DOWNSVIEW (ONTARIO)

Personal Author(s):

Report Date:

1972-08-29

Pagination or Media Count:

16.0

Abstract:

The ADPO ratios of single-sedimented liver mitochondria from heat-acclimated Sprague-Dawley rats were greater than control and cold-acclimated ratios heatcontrolcold. These differences were abolished by washing the mitochondria. EDTA in the homogenate reduced to a greater extent the magnesium and calcium content in mitochondria of cold- than heat-acclimated preparations. Elevation of magnesium in the medium increased ADPO values and reduced respiratory rates in all mitochondrial populations. During calcium respiration ADPO ratios were decreased significantly in cold-acclimated mitochondria. Author

Subject Categories:

  • Biochemistry
  • Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE