Accession Number:

AD0765471

Title:

Hemoglobin Function in Stored Blood: XIII. A Citrate-Adenine Preservative with Optimal pH to Maintain Red Cell 2,3-DPG (Function) and ATP (Viability).

Descriptive Note:

Interim rept.,

Corporate Author:

ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Report Date:

1973-04-19

Pagination or Media Count:

15.0

Abstract:

Increasing the pH by a 0.5 increment over the commonly used preservative, acid-citrate-dextrose ACD, results in a significant improvement in 2,3-DPG, with no significant loss in concentrations of ATP. The intermediate pH preservative, 6.0, also had 2,3-DPG concentrations which equalled those of the low pH preservatives from the 21st to 42nd day. A citrate-adenine preservative, with a pH between 5.5 and 6.0, would seem to be optimal for maintenance of hemoglobin function and red cell viability. Author

Subject Categories:

  • Medical Facilities, Equipment and Supplies

Distribution Statement:

APPROVED FOR PUBLIC RELEASE