Development of a Synthetic Polymer Burn Covering.
Progress rept. no. 3, 1 Jun-11 Aug 73.
DYNATECH R/D CO CAMBRIDGE MASS
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High molecular weight 140,000 poly-epsilon-caprolactone has been made using a bulk polymerization process. Poly-epsilon-caprolactone has been laminated to collagen film. When applied to a wound, collagen side down, the laminate successfully stimulated early coagulation and a fibrin network developed. Poly-epsilon-caprolactone has been laminated to nylon velour. A flash burn technique was established. Ploy-epsilon-caprolactone in a solvent solution was applied directly to the burn. Techniques were established for making porous poly-epsilon-caprolactone films which can be laminated to continuous films. A systematic program of epsilon-caprolactone ploymerizations has been initiated to determine the optimum reaction conditions. Poly-epsilon-caprolactone has been successfully bonded to two structured materials and the laminate tested in vivo.
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