Accession Number:

AD0762474

Title:

Biochemical and Transformation Studies of Pleuropneumoniae-Like (Mycoplasma) Organisms and L-Forms from Group A Streptococci.

Descriptive Note:

Final rept.,

Corporate Author:

ALBERT EINSTEIN MEDICAL CENTER PHILADELPHIA PA

Personal Author(s):

Report Date:

1973-06-12

Pagination or Media Count:

27.0

Abstract:

Studies have dealt with the L-forms from the group A streptococci, a group of bacteria pathogenic for man, and with the morphologically related mycoplasmas. They included investigations at the cellular and subcellular levels using whole cells, isolated membranes and cell-free systems and entailed the use of all techniques incidental to microbiology, biochemistry and chemistry. From these studies has come a better understanding of fundamental physiological and structural similarities and differences between the group A streptococci and their L-forms, between these L-forms and certain mycoplasmas, and of a possible biochemical mechanism for explaining the survival of these osmotically fragile L-forms in vivo. The role of the L-form in pathogenesis, however, remains only speculative. Modified author abstract

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE