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Effects of Symptomatic Treatment on Sustained Performance during Illness with 'Phebotomus' Fever.
Interim technical rept.,
LOUISVILLE UNIV KY PERFORMANCE RESEARCH LAB
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The results of the seventh BEID-7 and eighth BEID-8 in a series of long-term multiple-task performance studies of the behavioral effects of infectious diseases are reported. The 15-day BEID-7 study was conducted at the U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, with 10 volunteer subjects, nine of whom were infected with Phlebotomus Pappataci or Sandfly fever virus. Symptomatic treatment aspirin and Darvon was initiated for each subject at the onset of symptomatic illness and continued for a period of 48 hr. BEID-8 was a 12-day control study, conducted at the University of Louisville, in which 10 uninfected subjects received symptomatic treatment identical to that administered to the infected BEID-7 subjects. Subjects in both studies followed a work-rest schedule of 4 hr. on-duty, 4-hr. off, 4 on, and 12 off. Analyses of the sustained performance data indicate that essentially no decrements occurred during the period of illness and chemotherapy in BEID-7. The aspirin and Darvon treatment served to eliminate the 18 to 25 average decrement in performance typically found in previous studies of the behavioral effects of Phlebotomus fever. The symptomatic chemotherapy had no effect on the performance of the uninfected subjects in the BEID-8 control study. Author
APPROVED FOR PUBLIC RELEASE