Accession Number:

AD0758994

Title:

Interrelationship of Histamine Release and Vasoactive Peptides.

Descriptive Note:

Technical rept.,

Corporate Author:

OKLAHOMA UNIV HEALTH SCIENCES CENTER OKLAHOMA CITY

Personal Author(s):

• Johnson,A. R.
• Erdos,E. G.

Report Date:

1973-04-10

Pagination or Media Count:

15.0

Abstract:

Peptides release histamine from mast cells. Histamine releasers or histamine decrease the flow in perfused lung and cause edema. Perfusion fluids contain kininase II angiotensin I converting enzyme. Edema contains kininase I and II. Inhibition of kininase II converting enzyme of lung blocks compensatory rise in blood pressure in shocked dog by blocking angiotensin I liberation. Author

Descriptors:

• *CARDIOVASCULAR AGENTS
• *HISTAMINE
• PHARMACOLOGY
• IMMUNOLOGY
• METABOLISM
• PHYSIOLOGY
• ANAPHYLAXIS
• SHOCK(PATHOLOGY)
• ENZYMES
• LUNG
• BLOOD CIRCULATION

Subject Categories:

• Medicine and Medical Research
• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE