Interrelationship of Histamine Release and Vasoactive Peptides.
OKLAHOMA UNIV HEALTH SCIENCES CENTER OKLAHOMA CITY
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Peptides release histamine from mast cells. Histamine releasers or histamine decrease the flow in perfused lung and cause edema. Perfusion fluids contain kininase II angiotensin I converting enzyme. Edema contains kininase I and II. Inhibition of kininase II converting enzyme of lung blocks compensatory rise in blood pressure in shocked dog by blocking angiotensin I liberation. Author
- Medicine and Medical Research