Accession Number:

AD0757155

Title:

Gas-Liquid Chromatographic Assay of 1,2,3-Trimercaptopropane in Dimercaprol.

Descriptive Note:

Technical rept. Apr 68-Mar 72,

Corporate Author:

EDGEWOOD ARSENAL MD

Personal Author(s):

• Cooper,Aubrey E.
• Kondritzer,Albert A.

Report Date:

1973-03-01

Pagination or Media Count:

14.0

Abstract:

The report provides a description of studies conducted, using the technique of gas-liquid chromatography, to determine if 1,2,3-Trimercaptopropane TSH is present to an extent greater than 1.5 percent in lots of dimercaprol BAL, which is used in the formulation of FSN 6505-108-8500 Dimercaprol Injection, USP, 10 percent 5 cc. Satisfactory results were obtained using an 18-foot glass column, SE-30 liquid support, and isothermal operation. Author

Descriptors:

• (*THIOLS
• *GAS CHROMATOGRAPHY)
• IMPURITIES
• PROPANOLS

Subject Categories:

• Pharmacology
• Organic Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE