Accession Number:

AD0755851

Title:

Blood Flow Studies in Man in Shock.

Descriptive Note:

Final technical rept.,

Corporate Author:

GOTEBORG UNIV (SWEDEN)

Personal Author(s):

Report Date:

1972-08-01

Pagination or Media Count:

88.0

Abstract:

Acute normovolemic hemodilution in polycythemia vera increases or maintains capillary transport in skeletal muscle. Inorganic phosphate ion increases both flow and transport in human skeletal muscle. Afibrinogenemic dogs in shock show the same muscle-to-blood transport defect in skeletal muscle as dogs with normal fibrinogen levels, indicating that disseminated intravascular coagulation is not the cause ot this alteration in the microcirculation in skeletal muscle. Venous effluent from acutely traumatized muscle reveals an increase in PO2, PCO2, potassium ion, phosphate ion, lactic acid, pyruvic acid, osmotic pressure and kinins and a decrease in pH and no change in sodium ion. Trasylol given at the time of soft tissue trauma can prevent platelet trapping in the lungs. Trauma also causes a trapping of white cells in the lung which can be inhibited by Trasylol.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE