Red Blood Cell Density and Volume Changes in Men Exposed to Hypobaric Hyperoxia
Interim rept. 1 Jul 1970-15 Dec 1971
SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TX
Pagination or Media Count:
Eight volunteers were exposed to 100 O2 at 258 mm. Hg for 31 days. Blood samples were taken daily, and red cell RBC volume distributions were determined by Coulter counter--RBC density distributions, by the method of Danon and Marikovsky. RBC volume distribution varied in a cyclic fashion but exhibited no consistent, significant changes. After 4 to 6 days in the test environment, the RBC populations showed an increase in the proportion of dense cells and a trend of increasing senescence was evident for the remainder of the exposure period. Postexposure changes indicated the formation of new red cells.
- Stress Physiology