Accession Number:

AD0753581

Title:

Chemical Protection in Mixed Gamma-Neutron Irradiation with Different Neutron Contributions in the Absorbed Dose,

Descriptive Note:

Corporate Author:

DEFENCE RESEARCH INFORMATION CENTRE ORPINGTON (ENGLAND)

Personal Author(s):

• Vasin,M. V.
• Kozlov,V. A.

Report Date:

1972-11-01

Pagination or Media Count:

9.0

Abstract:

When the neutron component in mixed gamma-neutron irradiation drops to 25-30 the protective effect of AET S, beta-aminoethyl isothioronium bromidehydrobromide and cystamine is manifest to the same degree as in conditions of gamma- and X-ray radiation. The subject of the present investigation was the effectiveness of pharmacochemical protective substances as the neutron component increases. Experiments were carried out on non-pedigree white female mice weighing 19-22 g kept under normal animal-house conditions and fed on a standard diet. The compounds were AET, Cystafos monosodium beta-aminoethylthiophosphate, Cystamine, 5-MOT 5-methoxytryptamine, AET 5 MOT, and Cystafos 5-MOT.

Descriptors:

• *RADIOPROTECTIVE AGENTS
• *NEUTRONS
• PHARMACOLOGY
• AMINES
• ORGANIC SULFUR COMPOUNDS
• ORGANIC PHOSPHORUS COMPOUNDS
• RATS
• USSR

Subject Categories:

• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE