Accession Number:

AD0750230

Title:

Trimethoprim-Sulphamethoxazole in Acute Brucellosis

Descriptive Note:

Final rept.

Corporate Author:

NAVAL MEDICAL RESEARCH UNIT NO 3 FPO NEW YORK 09527

Report Date:

1971-01-01

Pagination or Media Count:

9.0

Abstract:

Eight patients with proved brucella infection were treated with trimethoprim-sulphamethoxazole. The dose varied from two to four tablets given twice daily for three weeks. Clinical response was rapid and all patients were asymptomatic and afebrile within two to seven days of starting therapy. Three patients relapsed clinically and bacteriologically within three weeks of ending treatment. It is suggested that the treatment be continued for at least six weeks to prevent relapses.

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE